" /> EGFR Inhibitor NRC-2694 Hydrochloride - CISMeF





Preferred Label : EGFR Inhibitor NRC-2694 Hydrochloride;

NCIt synonyms : EGFR Inhibitor NRC-2694 Monohydrochloride;

NCIt related terms : NRC-2694 HYDROCHLORIDE;

NCIt definition : The monohydrochloride salt form of NRC-2694, an orally bioavailable, small-molecule inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, EGFR inhibitor NRC-2694 binds to and inhibits EGFR, which prevents EGFR-mediated signaling and leads to cell death in EGFR-expressing tumor cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization.;

UNII : 6RZ8T2FCG6;

CAS number : 1172626-99-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1172626-99-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : NRC 2694-A; NRC-2694A;

NCI Metathesaurus CUI : CL1779253;

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08/05/2024


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