Preferred Label : Copper Cu 64 Abefolastat Tesaroxetan;
NCIt synonyms : 64Cu-SAR-bisPSMA; Copper Cu 64-SAR-bisPSMA; 64Cu SAR-bisPSMA; SAR-Bis-PSMA Cu-64; Copper Cu 64 SAR-bisPSMA;
NCIt related terms : ABEFOLASTAT TESAROXETAN CU-64;
NCIt definition : A radioconjugate composed of abefolastat tesaroxetan, two human prostate-specific
membrane antigen (PSMA) binding motifs linked to a SAR chelator, and labeled with
the positron emission tomography (PET) tracer copper Cu 64, with potential use as
a tracer for PSMA-expressing tumors during positron emission tomography (PET)/computed
tomography (CT). Upon administration of copper Cu 64 abefolastat tesaroxetan, the
PSMA binding motifs target and bind to PSMA-expressing tumor cells. Upon binding,
PSMA-expressing tumor cells can be detected during PET/CT imaging. PSMA, a tumor-associated
antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic
epithelial cells and overexpressed on prostate tumor cells.;
UNII : LK5NC9CE4C;
CAS number : 2254668-61-4;
NCI Metathesaurus CUI : CL1779267;
Origin ID : C187027;
UMLS CUI : C5670961;
Semantic type(s)
- concept_is_in_subset
- has_target
