Preferred Label : Copper Cu 64 SAR-bisPSMA;
NCIt synonyms : 64Cu-SAR-bisPSMA; Copper Cu 64-SAR-bisPSMA; 64Cu SAR-bisPSMA;
NCIt definition : A radioconjugate composed of two human prostate-specific membrane antigen (PSMA) binding
motifs linked to a SAR chelator and labeled with the positron emission tomography
(PET) tracer copper Cu 64, with potential use as a tracer for PSMA-expressing tumors
during positron emission tomography (PET)/computed tomography (CT). Upon administration
of copper Cu 64 SAR-bisPSMA, the PSMA binding motifs target and bind to PSMA-expressing
tumor cells. Upon binding, PSMA-expressing tumor cells can be detected during PET/CT
imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein,
is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate
tumor cells.;
NCI Metathesaurus CUI : CL1779267;
Origin ID : C187027;
UMLS CUI : C5670961;
Semantic type(s)
- concept_is_in_subset
- has_target
