Preferred Label : Selective Estrogen Receptor Degrader AND019;
NCIt synonyms : SERD AND019;
NCIt definition : An orally bioavailable selective estrogen receptor degrader/downregulator (SERD),
with potential antineoplastic activity. Upon oral administration, SERD AND019 specifically
targets and binds to the estrogen receptor (ER) and induces a conformational change
that results in ER degradation. This prevents ER-mediated signaling and inhibits both
the growth and survival of ER-expressing cancer cells.;
Molecule name : AND-019; AND 019;
NCI Metathesaurus CUI : CL1778591;
Origin ID : C186373;
UMLS CUI : C5667056;
Semantic type(s)
- concept_is_in_subset
- has_target
