High Grade Astrocytoma with Piloid Features - CISMeF
High Grade Astrocytoma with Piloid FeaturesNCIt concept
Preferred Label : High Grade Astrocytoma with Piloid Features;
NCIt synonyms : High-Grade Astrocytoma with Piloid Features; Anaplastic Astrocytoma with Piloid Features; Anaplastic Pilocytic Astrocytoma;
NCIt definition : An astrocytoma characterized by high-grade piloid and/or glioblastoma-like histological
features. It may occur anywhere in the central nervous system but most often arises
in the posterior fossa. Alterations in the following three pathways are responsible
for the pathogenesis of this tumor: MAPK pathway, retinoblastoma tumor suppressor
protein cell-cycle pathway, and telomere maintenance pathway.;