Ral GTPase-Activating Protein Subunit Beta

Preferred Label : Ral GTPase-Activating Protein Subunit Beta;

NCIt synonyms : Ral GTPase Activating Protein Non-Catalytic Subunit Beta; RALGAPB; p170;

NCIt definition : Ral GTPase-activating protein subunit beta (1494 aa, 167 kDa) is encoded by the human RALGAPB gene. This protein plays a role in RalGAP1- and RalGAP2-mediated activation of Ral family GTPases.;

NCIt note : Ral GTPase-activating protein subunit beta is a component of both the heterodimeric RalGAP1 complex with RALGAPA1 and of the heterodimeric RalGAP2 complex with RALGAPA2. Complex formation is required for activation of Ral family GTPases. (UniProt);

Details

Origin ID

C185716;

UMLS CUI

C3884217;

Automatic exact mappings (from CISMeF team)
- ATP binding cassette subfamily B member 1 [ORDO Gene]
- RALGAPB protein, human [MeSH Supplementary Concept]
- Ral GTPase activating protein non-catalytic subunit beta [HGNC gene]
- Ral gtpase-activating protein, noncatalytic subunit beta [OMIM gene]
- alpha-2-macroglobulin like 1 [ORDO Gene]
OMIM relation
- Ral gtpase-activating protein, noncatalytic subunit beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RALGAPB protein, human [MeSH Supplementary Concept]
- RALGAPB protein, human [MeSH concept]
gene_encodes_gene_product
- RALGAPB Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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