" /> SARS-CoV-2 3C-Like Proteinase Nsp5 - CISMeF





Preferred Label : SARS-CoV-2 3C-Like Proteinase Nsp5;

NCIt synonyms : M-pro; 3C-Like Proteinase Nsp5; Non-Structural Protein 5; 3C(L)pro; EC 3.4.22.69; Mpro; nsp5; C30 Endopeptidase; Severe Acute Respiratory Syndrome Coronavirus 2 3C-Like Proteinase Nsp5; SARS2 3C-Like Proteinase Nsp5; 3CLp; Main Protease; 3CL-PRO; 3C-Like Protease; SARS Coronavirus Main Proteinase;

NCIt definition : Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3C-like proteinase nsp5 (306 aa, 34 kDa) is encoded by the SARS-CoV-2 ORF1a and ORF1ab genes. This protein is involved in viral replication.;

NCIt note : SARS-CoV-2 3C-like proteinase nsp5 is comprised of amino acid residues 3264-3569 of the replicase polyprotein 1ab. (UniProt); SARS-CoV-2 3C-Like Proteinase Nsp5 is associated with two Swiss_Prot identifiers because it can be produced by proteolysis of both replicase polyprotein 1ab (pp1ab) and replicase polyprotein 1a (pp1a), which are encoded by the SARS-CoV-2 ORF1ab and ORF1a genes, respecitively.;

NCI Metathesaurus CUI : CL1772906;

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30/05/2025


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