Preferred Label : Allogeneic Anti-CD5 CAR T Cells;
NCIt synonyms : Donor-derived Anti-CD5 CAR T Cells; Allogeneic Anti-CD5 CAR-T Cells; Allogeneic CD5-targeting CAR T-cells; Donor-derived CD5 CAR T Cells;
NCIt definition : A preparation of allogeneic T-lymphocytes that have been genetically modified to express
a chimeric antigen receptor (CAR) specific for CD5, with potential immunomodulating
and antineoplastic activities. Upon administration, the allogeneic anti-CD5 CAR T
cells target and bind to CD5-expressing tumor cells, thereby inducing selective cytotoxicity
in CD5-expressing tumor cells. CD5 is a T-cell surface glycoprotein expressed on the
surface of normal T-cells and overexpressed on various B- and T-cell malignancies.;
NCI Metathesaurus CUI : CL1772559;
Origin ID : C184378;
UMLS CUI : C5669239;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
