Preferred Label : Microtubule-Associated Proteins 1A/1B Light Chain 3-I;
NCIt synonyms : LC3-I; MAP1LC3-I; LC3 I;
NCIt definition : Microtubule-associated proteins 1A/1B light chain 3-I (LC3-I) are cytoplasmic products
of the autophagy-dependent processing of microtubule-associated proteins 1A/1B light
chain 3 family proteins (LC3) by cysteine protease ATG4B. As autophagy progresses
LC3-I is further cleaved and processed via the conjugation of a phospholipid anchor
to form the membrane localized LC3-II.;
NCI Metathesaurus CUI : CL1772624;
Origin ID : C184321;
UMLS CUI : C5669204;
Semantic type(s)
- concept_is_in_subset
