NCIt definition : A human immunoglobulin G1 (IgG1) monoclonal antibody directed against the spike (S)
protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can
potentially be used for immunization against the Coronavirus disease 2019 (COVID-19).
Upon administration via inhalation, lomtegovimab specifically targets and binds to
the receptor-binding domain (RBD) of the S protein, thereby blocking viral attachment
and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the
progression of the disease and accelerate recovery, and may potentially provide temporary
protection against infection with SARS-CoV-2.;
UNII : 7EPY8J7EVF;
CAS number : 2550869-33-3;
Molecule name : BI-767551; BI 767551; BI 00767551; DZIF-10c;
Semantic type(s)