Zymosan - CISMeF

Preferred Label : Zymosan;

NCIt synonyms : ZM;

NCIt definition : An insoluble beta-1,3-glucan polysaccharide derived from, and structural component of, yeast cell walls, with potential immunostimulating activity. Upon administration, zymosan targets, binds to and activates certain Toll-like receptors, primarily TLR type 2 (TLR-2), on leukocytes and dectin-1 on macrophages. Activation of TLR2 and dectin-1 stimulates the release of pro-inflammatory mediators, and enhances innate immune responses.;

CAS number : 9010-72-4;

NCI Metathesaurus CUI : CL1771367;

Details

Origin ID

C183132;

UMLS CUI

C0043552;

Automatic exact mappings (from CISMeF team)
- zymosan A [MeSH concept]
Currated CISMeF NLP mapping
- zymosan [MeSH Descriptor]
- zymosan [Substance BNPC]
- zymosan [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- zymosan [MeSH Descriptor]
- zymosan [MeSH concept]
- zymosan [Substance BNPC]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- C-Type Lectin Domain Family 7 Member A [NCIt concept]
- Toll-Like Receptor 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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