Anagrelide Hydrochloride

Preferred Label : Anagrelide Hydrochloride;

NCIt definition : The hydrochloride salt of a synthetic quinazoline derivative, Anagrelide Hydrochloride reduces platelet production through a decrease in megakaryocyte maturation. Anagrelide inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. At therapeutic doses, it does not influence white cell counts or coagulation parameters. Anagrelide is used for treatment of essential thrombocythemia to reduce elevated platelet counts and the risk of thrombosis. (NCI04);

UNII : YTM763Y5C8;

CAS number : 823178-43-4;

Drug name : Agrylin;

Molecule name : BL-4162A; BMY-26538-01;

Details

Origin ID

C183131;

UMLS CUI

C0771907;

Currated CISMeF NLP mapping
- Anagrelide hydrochloride [SMS substance]
- Anagrelide hydrochloride (substance) [SNOMED CT concept]
- anagrelide hydrochloride [MeSH concept]
- anagrelide hydrochloride [Substance BNPC]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Anagrelide hydrochloride (substance) [SNOMED CT concept]
- anagrelide hydrochloride [MeSH concept]
- anagrelide hydrochloride [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Anagrelide [NCIt concept]
is_salt_form_of
- Anagrelide [NCIt concept]

Keyword's position in hierarchy(ies) :

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