" /> Interferon Beta-1A - CISMeF





Preferred Label : Interferon Beta-1A;

NCIt synonyms : Recombinant interferon beta-1a;

NCIt definition : A recombinant form of the endogenous cytokine human interferon (IFN) beta-1a, with antiproliferative, antiviral and immunomodulating activities. Upon administration, interferon beta-1a targets and binds to specific type I IFN receptors, which eventually results in the transcription and translation of genes containing an interferon-specific response element and leads to the production of various anti-viral proteins and modulates the production of various immune-modulating proteins. This reduces the production of certain pro-inflammatory cytokines while upregulating the anti-inflammatory cytokine interleukin 10 (IL-10), upregulates the expression of major histocompatibility (MHC) I proteins which allows for increased presentation of peptides derived from viral antigens, and activates CD8 T cells as well as other immune cells. Endogenous IFN-beta-1a is produced following viral infection and it plays a key role in innate immune response against viral pathogens.;

UNII : XRO4566Q4R;

CAS number : 145258-61-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 145258-61-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Avonex; Rebif;

Molecule name : BG9418;

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15/05/2024


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