Y593-Phosphorylated DDX5

Preferred Label : Y593-Phosphorylated DDX5;

NCIt synonyms : Y593 Phosphorylated-p68 RNA Helicase; Y593-Phosphorylated Probable ATP-Dependent RNA Helicase DDX5; pY593-DDX5; Y593-Phosphorylated p68; pY593-p68;

NCIt definition : A post-translationally modified form of probable ATP-dependent RNA helicase DDX5 (p68; DDX5) where the tyrosine (Y; Tyr) at residue 593 is phosphorylated. In tumor cells, platelet-derived growth factor-induced phosphorylation of DDX5 Y593 is associated with epithelial-mesenchymal transition (EMT) and resistance to TRAIL-induced apoptosis.;

NCI Metathesaurus CUI : CL1770629;

PubMed : 17018282; 17384675;

Details

Origin ID

C182133;

UMLS CUI

C5667326;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
related_to_genetic_biomarker
- DDX5 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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