Ursodiol - CISMeF

Preferred Label : Ursodiol;

NCIt synonyms : Ursodeoxycholic Acid; (3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid; UDCA;

NCIt definition : A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract.;

Alternative definition : NCI-GLOSS: A drug that is used to dissolve gallstones in people who can't have surgery to remove them. It is also being studied in the prevention of colorectal cancer. Ursodiol belongs to the family of drugs called anticholelithics.;

UNII : 724L30Y2QR;

InChIKey : RUDATBOHQWOJDD-UZVSRGJWSA-N;

CAS number : 128-13-2;

Drug name : Deursil; Actigall; URSO;

Chemical formula : C24H40O4;

NSC code : 657950; 683769;

ChEBI ID : CHEBI:9907;

Codes from synonyms : 05081; NSC0683769; CDR0000322234;

Details

Origin ID

C1818;

UMLS CUI

C0042105;

Automatic exact mappings (from CISMeF team)
- 2-methyl-3-(2-((4-nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester [MeSH Supplementary Concept]
- Ursodiol [ICHI extension code]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing ursodeoxycholic acid (medicinal product) [SNOMED CT concept]
- Ursodeoxycholic acid [ICD-11 Extension code]
- Ursodeoxycholic acid (substance) [SNOMED CT concept]
- ursodeoxycholic Acid [International Nonproprietary Name]
- ursodeoxycholic acid [ATC Code]
- ursodeoxycholic acid [Substance BNPC]
- ursodeoxycholic acid [MeSH concept]
- ursodeoxycholic acid [MeSH Descriptor]
- ursodeoxycholic acid [SNOMED Notion]
Validated automatic mappings to BTNT
- ursodeoxycholic acid [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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