Preferred Label : EGFR/HER2 Inhibitor TAS2940;
NCIt definition : An orally bioavailable, small molecule inhibitor of epidermal growth factor receptor
(EGFR) and human epidermal growth factor receptor 2 (HER2), with potential antineoplastic
activity. Upon oral administration, EGFR/HER2 inhibitor TAS2940 targets, binds to
and inhibits EGFR and HER2, which may result in the inhibition of tumor growth and
angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. EGFR and HER2 are
receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor
vascularization.;
Molecule name : TAS 2940; TAS-2940;
NCI Metathesaurus CUI : CL1664632;
Origin ID : C181795;
UMLS CUI : C5557270;
Semantic type(s)
- concept_is_in_subset
- has_target
