" /> Yttrium Y-90 Ibritumomab Tiuxetan - CISMeF





Preferred Label : Yttrium Y-90 Ibritumomab Tiuxetan;

NCIt synonyms : Y 90 Ibritumomab Tiuxetan; IDEC-Y2B8; Yttrium Y 90 Ibritumomab Tiuxetan;

NCIt related terms : yttrium Y90 ibritumomab tiuxetan; Y 90 Zevalin; IDEC-Y2B8 monoclonal antibody;

NCIt definition : A radioimmunotherapeutic agent consisting of a murine monoclonal anti-CD20 antibody (ibritumomab) linked by the chelator tiuxetan to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 ibritumomab tiuxetan binds to and specifically delivers beta radiation to CD20-expressing tumor cells, thereby minimizing the systemic effects of radiation.;

Alternative definition : NCI-GLOSS: A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. Y 90 ibritumomab tiuxetan is a type of radiopharmaceutical.;

UNII : QA846JAV5B;

NSC code : 710085;

Codes from synonyms : CDR0000579678; CDR0000579676; CDR0000046734; CDR0000046020;

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16/05/2024


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