HSP90 Peptide Vaccine AST-021p

Preferred Label : HSP90 Peptide Vaccine AST-021p;

NCIt synonyms : Therapeutic Cancer Vaccine AST-021p;

NCIt definition : A cancer vaccine containing a peptide antigen derived from a specific protein heat shock protein 90 (HSP90) generated by tumor cells, with potential immunostimulating and antineoplastic activities. Upon vaccination, the HSP90 peptide vaccine may activate the immune system to induce an immune response against HSP90-expressing tumor cells. Hsp90, a chaperone complex protein upregulated in a variety of tumor cell types, regulates the folding and degradation of many oncogenic signaling proteins.;

Molecule name : AST-021p; AST 021p;

NCI Metathesaurus CUI : CL1663337;

Details

Origin ID

C180678;

UMLS CUI

C5556552;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Heat Shock Protein 90 [NCIt concept]

Keyword's position in hierarchy(ies) :

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