" /> Clifutinib Besylate - CISMeF





Preferred Label : Clifutinib Besylate;

NCIt definition : The besylate salt form of clifutinib, an orally bioavailable, selective, small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2), with potential antineoplastic activity. Upon oral administration, clifutinib targets, binds to and inhibits the activity of FLT3. This inhibits the proliferation of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase (RTK), is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid leukemias.;

Molecule name : HEC-73543; HEC 73543;

NCI Metathesaurus CUI : CL1663045;

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12/05/2024


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