Arzoxifene - CISMeF

Preferred Label : Arzoxifene;

NCIt definition : A synthetic, aromatic derivative with anti-estrogenic properties. Similar to the agent raloxifene, arzoxifene binds to and interacts with estrogen receptors as a mixed estrogen agonist/antagonist. This agent exhibits greater bioavailability and higher anti-estrogenic potency in the breast than does raloxifene; it exhibits reduced estrogenicity in the uterus compared with either tamoxifen or raloxifene. Arzoxifene may have beneficial effects on bone and the cardiovascular system (NCI04);

UNII : E569WG6E60;

InChIKey : MCGDSOGUHLTADD-UHFFFAOYSA-N;

CAS number : 182133-25-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 182133-25-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : LY353381;

Chemical formula : C28H29NO4S;

Details

Origin ID

C1805;

UMLS CUI

C1100184;

Automatic exact mappings (from CISMeF team)
- LY 353381 [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- arzoxifene [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- arzoxifene [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Arzoxifene Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Arzoxifene Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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