NCIt definition : The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer
with antineoplastic properties. The polyglutamate residue increases the water solubility
of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel
alone. Paclitaxel promotes microtubule assembly and prevents microtubule depolymerization,
thus interfering with normal mitosis.;
Alternative definition : NCI-GLOSS: A form of the anticancer drug paclitaxel combined with a protein called
poliglumex that may have fewer side effects and work better than paclitaxel. It is
being studied in the treatment of breast cancer, ovarian cancer, lung cancer, and
other types of cancer. It belongs to the family of drugs called mitotic inhibitors.;
UNII : TQ64FZ98ZN;
CAS number : 263351-82-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 263351-82-2
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G-SRS /a ;
Drug name : Xyotax;
Molecule name : CT-2103;
Chemical formula : C10H16N2O7(C52H56N2O16)n(C5H7NO3)n;
NSC code : 724773;
Codes from synonyms : CDR0000045026; CDR0000512887; CDR0000468782; CDR0000270712;