Anti-HER2 Monoclonal Antibody QL1209

Preferred Label : Anti-HER2 Monoclonal Antibody QL1209;

NCIt definition : A humanized monoclonal antibody directed against the domain II of the extracellular domain of human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential antineoplastic activity. Upon administration, anti-HER2 monoclonal antibody QL1209 targets and binds to HER2 on HER2-expressing tumor cells. This prevents HER2-mediated signaling and may lead to an inhibition of proliferation in HER2-expressing tumor cells. HER2, a tyrosine kinase receptor, is overexpressed by many cancer cell types.;

Molecule name : QL-1209; QL 1209;

NCI Metathesaurus CUI : CL1661888;

Details

Origin ID

C179287;

UMLS CUI

C5555586;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Receptor Tyrosine-Protein Kinase erbB-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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