Preferred Label : Cultured Lentinula edodes Mycelia Extract;
NCIt synonyms : L. edodes Mycelia Extract AHCC; Yinuojin Ruanjiaonang; Lentinula edodes Mycelia Extract; ECLM; Standardized Extract of Cultured Lentinula edodes Mycelia; Cultured Lentinula edodes Mycelia Extract AHCC;
NCIt related terms : ACTIVE HEXOSE CORRELATED COMPOUND;
NCIt definition : An orally bioavailable capsule-based formulation of a standardized extract of cultured
Lentinula edodes (Shiitake mushroom) mycelia (ECLM), which is high in the polysaccharides
beta- and alpha-glucans, with potential antioxidant, immunomodulating and antineoplastic
activities. Upon oral administration, the cultured Lentinula edodes mycelia extract
activates the immune system, by binding to toll-like receptors (TLRs), specifically
TLR-4, and induces the activation of dendritic cells (DCs), natural killer (NK) cells,
macrophages and T-cells and the release of cytokines. This may clear human papillomavirus
(HPV) infections.;
UNII : S1W5KTD68Y;
CAS number : 249508-46-1;
Drug name : AHCC;
NCI Metathesaurus CUI : CL1661892;
Origin ID : C179283;
UMLS CUI : C5555582;
Semantic type(s)
- concept_is_in_subset
- has_target
