NCIt definition : A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with
prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic
activities. Upon administration of the autologous PC-specific antigens-pulsed DCs
injected subcutaneously near the inguinal lymph nodes, the DCs stimulate a specific
cytotoxic T-lymphocyte (CTL)-mediated immune response against the PC cells expressing
the antigens, resulting in tumor cell lysis.;