Autologous Ovarian Cancer-specific Antigens-pulsed Dendritic Cells Cellgram-DC

Preferred Label : Autologous Ovarian Cancer-specific Antigens-pulsed Dendritic Cells Cellgram-DC;

NCIt synonyms : Autologous Ovarian Cancer-specific Antigens-pulsed DCs Cellgram-DC; Cellgram-DC; Autologous Dendritic Cells Cellgram-DC Pulsed with Ovarian Cancer-specific Antigens;

NCIt definition : A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with ovarian cancer-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous administration of the autologous ovarian cancer-specific antigens-pulsed DCs Cellgram-DC near the lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the ovarian cancer cells expressing the antigens, resulting in tumor cell lysis.;

NCI Metathesaurus CUI : CL1661903;

Details

Origin ID

C179268;

UMLS CUI

C5555568;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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