" /> Personalized Peptides-loaded Autologous Dendritic Cell Vaccine - CISMeF





Preferred Label : Personalized Peptides-loaded Autologous Dendritic Cell Vaccine;

NCIt synonyms : Autologous Dendritic Cell Vaccine Loaded with Personalized Peptides; PEP-loaded Autologous DC Vaccine; PEP-DC Vaccine;

NCIt definition : A cell-based personalized cancer vaccine composed of autologous dendritic cells (DCs) loaded with the patient's own tumor-specific peptides, with potential immunostimulatory and antineoplastic activities. Upon administration of the personalized peptides (PEP)-loaded autologous DC vaccine, the DCs activate natural killer cells (NKs) and stimulate a cytotoxic T-lymphocyte (CTL)-mediated immune response against the patient's tumor cells expressing the PEPs, resulting in tumor cell lysis.;

NCI Metathesaurus CUI : CL1661921;

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30/07/2025


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