Preferred Label : FN1/FGFR1 Fusion Protein;
NCIt synonyms : Fibronectin 1-Fibroblast Growth Factor Receptor 1 Fusion Protein; Fibronectin 1/Fibroblast Growth Factor Receptor 1 Fusion Protein; Fibronectin-Fibroblast Growth Factor Receptor 1 Fusion Protein; Fibronectin/Fibroblast Growth Factor Receptor 1 Fusion Protein; FN1-FGFR1 Fusion Protein; FN1::FGFR1 Fusion Protein;
NCIt definition : A fusion protein encoded by the FN1/FGFR1 fusion gene. This protein is comprised of
the signal peptide and the N-terminal repeats required for cell surface binding, ECM
incorporation, fibril formation, and binding of collagen, fibrin, and fibronectin
of the fibronectin protein fused to the C-terminal sequences from the fibroblast growth
factor receptor 1 (FGFR1) protein, including two of the three extracellular ligand-binding
immunoglobulin-like C2 domains, the transmembrane domain and the intracellular tyrosine
kinase domain.;
NCI Metathesaurus CUI : CL1647805;
PubMed : 27443518;
Origin ID : C178365;
UMLS CUI : C5554982;
Semantic type(s)
- gene_encodes_gene_product
- related_to_genetic_biomarker
