Desmoglein-1 - CISMeF

Preferred Label : Desmoglein-1;

NCIt synonyms : Desmosomal Glycoprotein 1; DG1; Pemphigus Foliaceus Antigen; DSG1; Cadherin Family Member 4; DGI;

NCIt related terms : DESMOGLEIN 1;

NCIt definition : Desmoglein-1 (1049 aa, 114 kDa) is encoded by the human DSG1 gene. This protein is involved in cell-cell adhesion and keratinization.;

Alternative definition : CDISC: An antigen of the cell-cell adhesion protein encoded by the DSG1 gene. It can be considered as an autoantigen and is commonly associated with autoimmune diseases pemphigus foliaceus and pemphigus vulgaris.;

Details

Origin ID

C177652;

UMLS CUI

C5444214;

Automatic exact mappings (from CISMeF team)
- Dentinogenesis imperfecta [ORDO Disease]
- Desmoglein 1 [LOINC component]
- Desmoglein 1 [OMIM gene]
- desmoglein 1 [MeSH Descriptor]
- desmoglein 1 [MeSH concept]
- desmoglein 1 [ORDO Gene]
- desmoglein 1 [HGNC gene]
OMIM relation
- Desmoglein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- DSG1 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Desmosome [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cadherin Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Cell Adhesion Process [NCIt concept]
- Keratinization [NCIt concept]

Keyword's position in hierarchy(ies) :

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