Eniluracil - CISMeF

Preferred Label : Eniluracil;

NCIt synonyms : 5-Fluorouracil Enhancer; 5-Ethynyl-2,4(1H,3H)-pyrimidinedione;

NCIt related terms : 5-ethynyluracil; ethynyluracil;

NCIt definition : An orally-active fluoropyrimidine analogue. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU.;

Alternative definition : NCI-GLOSS: An anticancer drug that increases the effectiveness of fluorouracil.;

UNII : 2E2W0W5XIU;

InChIKey : JOZGNYDSEBIJDH-UHFFFAOYSA-N;

CAS number : 59989-18-3;

Molecule name : 776C85; GW776; PCS-6422; PCS 6422;

Chemical formula : C6H4N2O2;

NSC code : 687296;

Codes from synonyms : NSC0687296; 50533; CDR0000045545; CDR0000045526;

Details

Origin ID

C1773;

UMLS CUI

C0098361;

Currated CISMeF NLP mapping
- eniluracil [MeSH concept]
- eniluracil [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- eniluracil [MeSH Supplementary Concept]
- eniluracil [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Dihydropyrimidine Dehydrogenase [NADP(+)] [NCIt concept]
is_component_of_chemotherapy_regimen
- Eniluracil/Fluorouracil [NCIt concept]
- Eniluracil/Fluorouracil/Leucovorin Calcium [NCIt concept]
- Eniluracil/Fluorouracil/Oxaliplatin [NCIt concept]
- Ethynyluracil/Fluorouracil/Leucovorin Calcium [NCIt concept]

Keyword's position in hierarchy(ies) :

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