Linker for Activation of T-Cells Family Member 1

Preferred Label : Linker for Activation of T-Cells Family Member 1;

NCIt synonyms : LAT1; 36 kDa Phospho-Tyrosine Adaptor Protein; LAT; p36-38; pp36; 36 kDa Phospho-Tyrosine Adapter Protein;

NCIt definition : Linker for activation of T-cells family member 1 (262 aa, 28 kDa) is encoded by the human LAT gene. This protein plays a role in the positive regulation of immune receptor-dependent signaling pathways.;

Details

Origin ID

C176440;

UMLS CUI

C5444101;

Automatic exact mappings (from CISMeF team)
- 5'-((N-(2-decanoylamino-3-hydroxy-3-phenylpropyloxycarbonyl)glycyl)amino)-5'-deoxyuridine [MeSH Supplementary Concept]
- Linker for activation of t cells [OMIM gene]
- Origin recognition complex, subunit 3 [OMIM gene]
- PP36 [MeSH concept]
- Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 [OMIM gene]
- linker for activation of T cells [ORDO Gene]
- withholding treatment [MeSH Descriptor]
OMIM relation
- Linker for activation of t cells [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- LAT Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_expressed_in_tissue
- Splenic Tissue [NCIt concept]
- Thymic Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Mast Cell [NCIt concept]
- Plasma Membrane [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
gene_product_has_biochemical_function
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Class I PI3K Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- JNK Signaling in the CD4+ TCR Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
gene_product_plays_role_in_biological_process
- Immunity [NCIt concept]
- Inflammatory Response [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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