Preferred Label : Pegulicianine Acetate;
NCIt related terms : Cathepsin-Activatable Cy5 Fluorescent Imaging Probe LUM015;
NCIt definition : A cathepsin-activatable fluorescent probe with imaging activity. The cathepsin-activatable
fluorescent probe LUM015 contains the Cy5 fluorophore linked, via a pan-cathepsin
protease cleavable peptide, to a fluorescent quencher. Upon injection, the peptide
in LUM015 can be cleaved by cathepsins overexpressed by tumor cells, which releases
the quencher and activates the fluorophore. Upon imaging, tumor cells expressing cathepsin
family proteases can be detected.;
UNII : F3F6208UMT;
CAS number : 2230217-18-0;
Molecule name : LUM015;
NCI Metathesaurus CUI : CL1413247;
Origin ID : C175839;
UMLS CUI : C5446784;
Semantic type(s)
- concept_is_in_subset
- has_target
