RPS6KA4 wt Allele

Preferred Label : RPS6KA4 wt Allele;

NCIt synonyms : MSK2; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 4 Gene; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 4 Gene; Ribosomal Protein S6 Kinase, 90-kD, 4 Gene; Ribosomal Protein S6 Kinase A4 wt Allele; RSKB; RSK-B; S6K-alpha-4;

NCIt definition : Human RPS6KA4 wild-type allele is located in the vicinity of 11q13.1 and is approximately 13 kb in length. This allele, which encodes ribosomal protein S6 kinase alpha-4 protein, plays a role in mitogen- and stress-induced phosphorylation of target proteins.;

NCI Metathesaurus CUI : CL1412948;

GenBank Accession Number : AJ010119;

Details

Origin ID

C175645;

UMLS CUI

C5443944;

Automatic exact mappings (from CISMeF team)
- Antigen defined by monoclonal antibody t87 [OMIM Phenotype]
- Ribosomal protein s6 kinase a4 [OMIM gene]
OMIM relation
- Ribosomal protein s6 kinase a4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q13.1 [NCIt concept]
gene_is_element_in_pathway
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Histone Modification [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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