NCIt definition : A protein in which the coding region of two genes have become in-frame and co-continuous.
Fusion proteins can be formed by chromosomal breakage and/or recombination and also
can be experimentally created using recombinant DNA techniques.;
Alternative definition : NCI-GLOSS: A protein made from a fusion gene, which is created by joining parts of
two different genes. Fusion genes may occur naturally in the body by transfer of DNA
between chromosomes. For example, the BCR-ABL gene found in some types of leukemia
is a fusion gene that makes the BCR-ABL fusion protein. Fusion genes and proteins
can also be made in the laboratory by combining genes or parts of genes from the same
or different organisms.;