SSX Protein Family

Preferred Label : SSX Protein Family;

NCIt synonyms : SSX Family; Synovial Sarcoma, X Breakpoint Family; SSX Family Protein; Synovial Sarcoma X Breakpoint Protein; SSX; Synovial Sarcoma X Chromosome Breakpoint Protein;

NCIt related terms : SSX Antigen;

NCIt definition : A family of cancer/testis antigen proteins encoded by genes located on the short arm of the X chromosome within Xp11.22-Xp11.23. The initial members of this family were identified as fusion partners with either SS18 protein or SS18L protein in synovial sarcoma. SSX proteins play a role in the modulation of gene transcription and contain an N-terminal Krueppel-associated box (KRAB) domain and a C-terminal SSX repression domain (SSXRD).;

NCI Metathesaurus CUI : CL1413013;

Details

Origin ID

C175566;

UMLS CUI

C0298321;

Automatic exact mappings (from CISMeF team)
- synovial sarcoma X breakpoint proteins [MeSH Supplementary Concept]
- synovial sarcoma X breakpoint proteins [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- synovial sarcoma X breakpoint proteins [MeSH Supplementary Concept]
- synovial sarcoma X breakpoint proteins [MeSH concept]
is_chemical_classification_of_gene_product
- Protein SSX1 [NCIt concept]
- Protein SSX2 [NCIt concept]
- Protein SSX4 [NCIt concept]

Keyword's position in hierarchy(ies) :

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