Preferred Label : TAEK-VAC-HerBy Vaccine;
NCIt synonyms : TAEK-VAC-HerBy;
NCIt definition : A cancer vaccine targeting the tumor-associated antigen (TAA) HER-2/neu (ErbB-2),
with potential immunomodulating and antineoplastic activities. Upon administration,
TAEK-VAC-HerBy vaccine may induce a cytotoxic T-lymphocyte (CTL)-mediated immune response
against tumor cells expressing the HER-2/neu antigen, which may result in the inhibition
of proliferation in Her-2/neu-expressing tumor cells. Her-2/neu, a member of the epidermal
growth factor receptor (EGFR) family of tyrosine kinases, is overexpressed in various
tumor cell types.;
NCI Metathesaurus CUI : CL1412873;
Origin ID : C175510;
UMLS CUI : C5446584;
Semantic type(s)
- concept_is_in_subset
- has_target
