" /> Anti-CD4 CAR T-cells - CISMeF





Preferred Label : Anti-CD4 CAR T-cells;

NCIt synonyms : CD4 CAR T Cells; CD4-specific CAR T Cells;

NCIt definition : A preparation of T-lymphocytes that have been genetically modified and transduced with a lentiviral vector expressing a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD4 and containing, as of yet undisclosed co-stimulatory signaling domains, with potential immunostimulating and antineoplastic activities. Upon administration, anti-CD4 CAR T-cells target and bind to CD4-expressing tumor cells, thereby inducing selective toxicity in CD4-expressing tumor cells. CD4 antigen is expressed in CD4-positive T cell lymphomas.;

NCI Metathesaurus CUI : CL1411978;

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01/11/2024


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