Oncogene FOS - CISMeF

Preferred Label : Oncogene FOS;

NCIt synonyms : FOS; FBJ Murine Osteosarcoma Oncogene;

CISMeF acronym : FOS;

NCIt definition : Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene c-fos encodes a nuclear protein that dimerizes with Jun via a zipper motif to form the transcription factor AP1 and is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-3 on the long arm of chromosome 14.;

NCI Metathesaurus CUI : CL414318;

GenBank Accession Number : NM_005252;

Details

Origin ID

C17440;

UMLS CUI

C5441949;

Automatic exact mappings (from CISMeF team)
- Fos proto-oncogene, AP-1 transcription factor subunit [ORDO Gene]
- Fos protooncogene, ap1 transcription factor subunit [OMIM gene]
- fructooligosaccharide [Artificial nutrition thesaurus concept]
- genes, fos [MeSH concept]
- genes, fos [MeSH Descriptor]
False automatic mappings
- Following (attribute) [SNOMED CT concept]
OMIM relation
- Fos protooncogene, ap1 transcription factor subunit [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Fos proto-oncogene, AP-1 transcription factor subunit [HGNC gene]
- Fos protooncogene, ap1 transcription factor subunit [OMIM gene]
- v-fos genes [MeSH concept]
allele_in_chromosomal_location
- 14q24.3 [NCIt concept]
gene_encodes_gene_product
- FOS Oncoprotein [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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