Preferred Label : Histone H3 Trimethyl Lys28;
NCIt synonyms : H3K28me3; Histone H3 Trimethyl Lysine 28;
NCIt related terms : H3K27me3;
NCIt definition : A post-translationally modified form of histone H3 where the lysine residue at position
28 is trimethylated. This modification is associated with formation of heterochromatin
and polycomb repressive complex 1 (PRC1).;
NCIt note : Even though the literature refers to lysine 27 methylation or amino acid variation/mutation,
RefSeq indicates that the lysine is located at amino acid position 28 in histone H3.
(see https://link.springer.com/article/10.1007/s00401-018-1867-2);
NCI Metathesaurus CUI : CL1407746;
Origin ID : C174110;
UMLS CUI : C5420594;
Semantic type(s)
- concept_is_in_subset
- related_to_genetic_biomarker
