Histone H3 Trimethyl Lys9

Preferred Label : Histone H3 Trimethyl Lys9;

NCIt synonyms : Histone H3 Trimethyl Lysine 9; Histone H3 Trimethyl Lysine 10; Histone H3 Trimethyl Lys10;

NCIt related terms : H3K9me3;

NCIt definition : A post-translationally modified form of histone H3 where the lysine residue at position 9 is trimethylated. This modification is associated with heterochromatin formation and plays a role in embryonic stem cell lineage commitment and maintenance of lineage fidelity.;

NCIt note : Even though the literature refers to lysine 9 methylation/other modification or amino acid variation/mutation, RefSeq indicates that the lysine is located at amino acid position 10 in histone H3. (see also https://link.springer.com/article/10.1007/s00401-018-1867-2);

NCI Metathesaurus CUI : CL1407747;

Details

Origin ID

C174109;

UMLS CUI

C5420593;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
related_to_genetic_biomarker
- Histone H3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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