Imlunestrant - CISMeF

Preferred Label : Imlunestrant;

NCIt synonyms : SERD LY3484356; Selective Estrogen Receptor Degrader LY3484356;

NCIt definition : An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, imlunestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that results in ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells.;

UNII : 9CXQ3PF69U;

CAS number : 2408840-26-4;

Molecule name : LY-3484356; LY 3484356;

NCI Metathesaurus CUI : CL1407918;

Details

Origin ID

C174042;

UMLS CUI

C5565130;

Automatic exact mappings (from CISMeF team)
- Imlunestrant [MeSH Supplementary Concept]
- Imlunestrant [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Imlunestrant [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Estrogen Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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