NCIt definition : A neutralizing human monoclonal antibody directed against the spike (S) protein of
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially
be used for immunization against Coronavirus disease 2019 (COVID-19). Upon administration
of anti-COVID-19 S protein monoclonal antibody STI-1499, this agent specifically targets
and binds to the S1 subunit of the SARS-CoV-2 S protein, thereby blocking viral attachment
and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the
progression of the disease and accelerate recovery, and may potentially provide temporary
protection against infection with SARS-CoV-2. S-protein, usually found on the surface
of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2
virus.;
Semantic type(s)