NCIt definition : The hydrochloride salt form of histamine, with potential immunomodulatory and antineoplastic
activities. Upon administration, histamine targets, binds to and activates histamine
receptors. Depending on the amount of histamine administered and the type of receptor
that is activated, histamine may exert a wide variety of activities. These can range
from pro-tumorigenic to anti-tumor effects and may modulate the immune system to exert
anti-tumor immune effects or may contribute to an inflammatory response.;
Alternative definition : NCI-GLOSS: A substance being studied in the treatment of some types of cancer and
other conditions. When used together with interleukin-2, histamine dihydrochloride
may help some immune cells find and kill tumor cells. It is a type of biological response
modifier.;
UNII : 3POA0Q644U;
InChIKey : PPZMYIBUHIPZOS-UHFFFAOYSA-N;
CAS number : 56-92-8;
Drug name : Maxamine; Ceplene;
Chemical formula : C5H9N3.2HCl;
NSC code : 257873;
Codes from synonyms : NSC0257873; CDR0000579876; CDR0000045579; 03787; 120274;