Preferred Label : Interleukin-12-Fc Fusion Protein DF6002;
NCIt synonyms : IL-12-Fc Fusion Protein DF6002;
NCIt definition : A fusion protein composed of human interleukin-12 (IL-12) fused to a Fc fragment,
with potential immunomodulatory and antineoplastic activities. Upon administration
of IL-12-Fc fusion protein DF6002, the IL-12 moiety binds to the IL-12 receptor. This
may activate the immune system by promoting the secretion of interferon-gamma, activating
natural killer cells (NKs), and inducing cytotoxic T-lymphocyte (CTL) responses, which
may result in both decreased tumor cell proliferation and enhanced immune-mediated
destruction of tumor cells.;
Molecule name : DF-6002; DF 6002;
NCI Metathesaurus CUI : CL1407203;
Origin ID : C173371;
UMLS CUI : C5417965;
Semantic type(s)
- concept_is_in_subset
- has_target
