Androgen Receptor Degrader CC-94676

Preferred Label : Androgen Receptor Degrader CC-94676;

NCIt synonyms : AR Degrader CC-94676;

NCIt related terms : CC-94676;

NCIt definition : An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon administration, AR degrader CC-94676 causes degradation of AR, prevents AR-mediated signaling and inhibits the proliferation of AR-overexpressing tumor cells. AR plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC).;

UNII : VA228VR2DI;

Molecule name : CC 94676; CC-94676;

NCI Metathesaurus CUI : CL1407191;

Details

Origin ID

C173364;

UMLS CUI

C5417962;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Androgen Receptor [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Inhibition of Cell Proliferation [NCIt concept]
- Translational Repression [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Androgen Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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