NCIt synonyms : AR Degrader CC-94676; Androgen Receptor Degrader CC-94676;
NCIt definition : An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic
activity. Upon administration, gridegalutamide causes degradation of AR, prevents
AR-mediated signaling and inhibits the proliferation of AR-overexpressing tumor cells.
AR plays a key role in tumor cell proliferation in castration-resistant prostate cancer
(CRPC).;
UNII : VA228VR2DI;
CAS number : 2446929-86-6;
Molecule name : CC 94676; CC-94676; CC 1083611; BMS-986365; BMS 986365; BMS-986409; CEL 010355; BMS 986409; CEL-010355; CC-1083611;