Preferred Label : Anti-HER2 Antibody Conjugated Natural Killer Cells ACE1702;
NCIt synonyms : Anti-HER2 NK Cells ACE1702; Anti-HER2 Conjugated NK Cells ACE1702; Anti-HER2 Antibody Natural Killer Cell Conjugate ACE1702; Anti-HER2 oNK Cells; Anti-HER2 Antibody Conjugated NK Cells ACE1702;
NCIt definition : An off-the-shelf preparation of natural killer (NK) cells conjugated to a monoclonal
antibody targeting human epidermal growth factor receptor 2 (EGFR2; HER2; ErbB2),
with potential antineoplastic activity. Upon administration of anti-HER2 antibody
conjugated natural killer cells ACE1702, the antibody moiety targets and binds to
HER2 on tumor cells, which may lead to cell lysis of HER2-expressing tumor cells by
the NK cells. HER2, a tyrosine kinase receptor, is overexpressed by many cancer cell
types.;
Molecule name : ACE-1702; ACE 1702;
NCI Metathesaurus CUI : CL1406967;
Origin ID : C173076;
UMLS CUI : C5417957;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
