Preferred Label : Galidesivir Hydrochloride;
NCIt definition : The hydrochloride salt form of galidesivir, an adenosine analog and RNA polymerase
inhibitor, with potential broad-spectrum antiviral activity. Upon administration,
galidesivir is metabolized to its monophosphate form, which is then converted into
the active triphosphate nucleotide. Galidesivir triphosphate binds to viral RNA-dependent
RNA polymerase (RdRp) and gets incorporated into the growing viral RNA strand, which
leads to premature chain termination. This prevents viral transcription and replication.;
UNII : 1EL1K52SH1;
InChIKey : PCCHVYNGFMEGIG-QPAIBFMUSA-N;
CAS number : 222631-44-9;
Molecule name : BCX4430 Hydrochloride;
NCI Metathesaurus CUI : CL1406703;
Origin ID : C172614;
UMLS CUI : C5419740;
Semantic type(s)
- concept_is_in_subset
