Galidesivir - CISMeF

Preferred Label : Galidesivir;

NCIt synonyms : Immucillin-A;

NCIt definition : An adenosine analog and RNA polymerase inhibitor, with potential broad-spectrum antiviral activity. Upon administration, galidesivir is metabolized to its monophosphate form, which is then converted into the active triphosphate nucleotide. Galidesivir triphosphate binds to viral RNA-dependent RNA polymerase (RdRp) and gets incorporated into the growing viral RNA strand, which leads to premature chain termination. This prevents viral transcription and replication.;

UNII : OLF97F86A7;

InChIKey : AMFDITJFBUXZQN-KUBHLMPHSA-N;

CAS number : 249503-25-1;

Molecule name : BCX-4430; BCX 4430;

Details

Origin ID

C172613;

UMLS CUI

C1870231;

Currated CISMeF NLP mapping
- galidesivir [MeSH Supplementary Concept]
- galidesivir [MeSH concept]
- galidesivir [COVID-19 Thesaurus concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- galidesivir [MeSH Supplementary Concept]
- galidesivir [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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