NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the
endogenous cytokine Flt3. Flt3 ligand binds to the Flt3 tyrosine kinase receptor and,
synergistically with other growth factors, stimulates the proliferation and mobilization
of bone marrow precursor cells, including CD34 cells, and dendritic cells. When proteolytically
cleaved, the transmembrane isoform of Flt3 ligand generates the soluble form soluble
Flt3 ligand, which is also biologically active.;
Alternative definition : NCI-GLOSS: A drug that increases the number of immune cells and may stimulate the
immune system to kill cancer cells.;