" /> Recombinant Flt3 Ligand - CISMeF





Preferred Label : Recombinant Flt3 Ligand;

NCIt synonyms : Flt3-Ligand; FLT3 Ligand; FLT 3 Ligand; Flt3L; Therapeutic Flt3 Ligand; rhuFlt3L;

NCIt related terms : CDX-301;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine Flt3. Flt3 ligand binds to the Flt3 tyrosine kinase receptor and, synergistically with other growth factors, stimulates the proliferation and mobilization of bone marrow precursor cells, including CD34 cells, and dendritic cells. When proteolytically cleaved, the transmembrane isoform of Flt3 ligand generates the soluble form soluble Flt3 ligand, which is also biologically active.;

Alternative definition : NCI-GLOSS: A drug that increases the number of immune cells and may stimulate the immune system to kill cancer cells.;

UNII : SP24YIT5YZ;

CAS number : 2179360-80-4;

Drug name : Mobist; Mobista;

Molecule name : CDX-301;

NSC code : 696599;

Codes from synonyms : CDR0000045966;

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30/05/2025


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