Voriconazole - CISMeF

Preferred Label : Voriconazole;

NCIt synonyms : (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol;

NCIt definition : A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04);

Alternative definition : NCI-GLOSS: A drug that treats infections caused by fungi.;

UNII : JFU09I87TR;

InChIKey : BCEHBSKCWLPMDN-MGPLVRAMSA-N;

CAS number : 137234-62-9;

Drug name : Vfend;

Chemical formula : C16H14F3N5O;

ChEBI ID : CHEBI:10023;

Codes from synonyms : CDR0000045544; 544;

Details

Origin ID

C1707;

UMLS CUI

C0393080;

Currated CISMeF NLP mapping
- Voriconazole [MeSH Descriptor]
- Voriconazole [Substance BNPC]
- Voriconazole [ICD-11 Extension code]
- Voriconazole [SMS substance]
- Voriconazole [LOINC component]
- Voriconazole (substance) [SNOMED CT concept]
- voriconazole [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing voriconazole (medicinal product) [SNOMED CT concept]
- Voriconazole [MeSH Descriptor]
- Voriconazole [Substance BNPC]
- Voriconazole [LOINC component]
- Voriconazole (substance) [SNOMED CT concept]
- voriconazole [ATC Code]
- voriconazole [MeSH concept]
Validated automatic mappings to BTNT
- voriconazole [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Interferon Gamma/Voriconazole [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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