HRAS Gene - CISMeF

Preferred Label : HRAS Gene;

NCIt synonyms : HRas Proto-Oncogene, GTPase Gene;

NCIt related terms : H-ras gene; HRAS;

CISMeF acronym : HRAS;

NCIt definition : This gene plays a role in signal transduction and cellular communication.;

Alternative definition : NCI-GLOSS: A gene that may cause cancer when it is mutated (changed). The Hras gene makes the HRAS protein, which is involved in cell signaling pathways, cell growth, and apoptosis (cell death). Agents that block the actions of the mutated Hras gene or its protein in cancer cells may stop the growth of cancer.;

Codes from synonyms : CDR0000661988; CDR0000661987;

Details

Origin ID

C17060;

UMLS CUI

C0079471;

Automatic exact mappings (from CISMeF team)
- H-ras genes [MeSH concept]
- HRAS gene [LOINC component]
- HRas proto-oncogene, GTPase [ORDO Gene]
- Hras protooncogene, gtpase [OMIM gene]
- genes, ras [MeSH Descriptor]
HGNC gene
- HRas proto-oncogene, GTPase [HGNC gene]
OMIM relation
- Hras protooncogene, gtpase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- HRAS gene [LOINC component]
- HRas proto-oncogene, GTPase [HGNC gene]
- Hras protooncogene, gtpase [OMIM gene]
concept_is_in_subset
- CCPS Genetics Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Reference Gene Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Childhood Cancer Predisposition Study Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
gene_associated_with_disease
- Oral Cavity Squamous Cell Carcinoma [NCIt concept]
- Thyroid Gland Follicular Carcinoma [NCIt concept]
gene_encodes_gene_product
- GTPase HRas [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_abnormality
- HRAS Gene Amplification [NCIt concept]
gene_involved_in_molecular_abnormality
- Activating HRAS Mutation [NCIt concept]
- HRAS Gene Amplification [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- HRAS NM_005343.3:c.35G>A [NCIt concept]
- HRAS NM_005343.3:c.35G>T [NCIt concept]
- HRAS NM_005343.3:c.35_36delinsAT [NCIt concept]
- HRAS NM_005343.3:c.35_36delinsTA [NCIt concept]
- HRAS NP_005334.1:p.G12D [NCIt concept]
- HRAS NP_005334.1:p.G12V [NCIt concept]
- HRAS NP_005334.1:p.G12X [NCIt concept]
- HRAS NP_005334.1:p.G13X [NCIt concept]
- HRAS NP_005334.1:p.Q61X [NCIt concept]
- HRAS Protein Variant [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Costello Syndrome [NCIt concept]
gene_mapped_to_disease
- Costello Syndrome [NCIt concept]
gene_plays_role_in_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]
genetic_biomarker_related_to
- Activating HRAS Mutation [NCIt concept]
- Activating RAS Mutation [NCIt concept]
- Costello Syndrome [NCIt concept]
- HRAS Gene Mutation Negative [NCIt concept]
- HRAS Mutation Analysis [NCIt concept]
- HRAS Overexpression Positive [NCIt concept]
- HRAS Positive [NCIt concept]
- Non-synonymous RAS Family Gene Mutation [NCIt concept]
- Oncogene H-Ras [NCIt concept]
- RAS Family Gene Mutation [NCIt concept]
- RAS Family Protein Variant [NCIt concept]
- RAS Wild Type [NCIt concept]
- RAS/BRAF/NF1 Triple Wild Type [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients