Preferred Label : Flotufolastat F-18 Gallium;
NCIt synonyms : rhPSMA-7.3 (18F); Fluorine-18 rhPSMA-7.3; (18F)-rhPSMA-7.3; 18FrhPSMA-7.3; F-18-rhPSMA-7.3; Fluorine F 18 radiohybrid PSMA-7.3; 18F-rhPSMA-7.3; Fluorine F 18 rhPSMA-7.3;
NCIt definition : A radiohybrid prostate specific membrane antigen (rhPSMA) ligand, rhPSMA-7.3, labeled
with the radioisotope fluorine F 18, with potential imaging activity using positron
emission tomography/computed tomography (PET/CT) or positron emission tomography/magnetic
resonance imaging (PET/MRI). Upon administration of flotufolastat F-18 gallium, the
rhPSMA-7.3 moiety targets and binds to PSMA-expressing tumor cells. This allows for
visualization of PSMA-expressing cells upon imaging. PSMA, a tumor-associated antigen
(TAA) and type II transmembrane protein, is expressed on the membrane of prostatic
epithelial cells and strongly overexpressed in prostate cancer (PCa) cells, with its
level rising with increasing tumor differentiation and in hormone-refractory cancers.;
UNII : XD423NK2WO;
CAS number : 2305081-64-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2305081-64-3
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G-SRS /a ;
NCI Metathesaurus CUI : CL1378660;
Origin ID : C168738;
UMLS CUI : C5783385;
Semantic type(s)
- concept_is_in_subset
- has_target
